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A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism in Drosophila melanogaster photoreceptors

The vesicular adenosine triphosphatase (v-ATPase) is a proton pump that acidifies intracellular compartments. In addition, mutations in components of the membrane-bound v-ATPase V0 sector cause acidification-independent defects in yeast, worm, fly, zebrafish, and mouse. In this study, we present a d...

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Detalles Bibliográficos
Autores principales: Williamson, W. Ryan, Wang, Dong, Haberman, Adam S., Hiesinger, P. Robin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878941/
https://www.ncbi.nlm.nih.gov/pubmed/20513768
http://dx.doi.org/10.1083/jcb.201003062