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Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model
BACKGROUND: Overexpression and abnormal accumulation of aggregated α-synuclein (αS) have been linked to Parkinson's disease (PD) and other synucleinopathies. αS can misfold and adopt a variety of morphologies but recent studies implicate oligomeric forms as the most cytotoxic species. Both gene...
Autores principales: | Wang, Min S, Boddapati, Shanta, Emadi, Sharareh, Sierks, Michael R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879277/ https://www.ncbi.nlm.nih.gov/pubmed/20433710 http://dx.doi.org/10.1186/1471-2202-11-57 |
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