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Preparation and topology of the Mediator middle module

Mediator is the central coactivor complex required for regulated transcription by RNA polymerase (Pol) II. Mediator consists of 25 subunits arranged in the head, middle, tail and kinase modules. Structural and functional studies of Mediator are limited by the availability of protocols for the prepar...

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Detalles Bibliográficos
Autores principales: Koschubs, Tobias, Lorenzen, Kristina, Baumli, Sonja, Sandström, Saana, Heck, Albert J. R., Cramer, Patrick
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879511/
https://www.ncbi.nlm.nih.gov/pubmed/20123732
http://dx.doi.org/10.1093/nar/gkq029