Cargando…
Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1
The REF/ALY mRNA export adaptor binds TAP/NXF1 via an arginine-rich region, which overlaps with its RNA-binding domain. When TAP binds a REF:RNA complex, it triggers transfer of the RNA from REF to TAP. Here, we have examined the effects of arginine methylation on the activities of the REF protein i...
Autores principales: | Hung, Ming-Lung, Hautbergue, Guillaume M., Snijders, Ambrosius P. L., Dickman, Mark J., Wilson, Stuart A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879514/ https://www.ncbi.nlm.nih.gov/pubmed/20129943 http://dx.doi.org/10.1093/nar/gkq033 |
Ejemplares similares
-
UIF, a New mRNA Export Adaptor that Works Together with REF/ALY, Requires FACT for Recruitment to mRNA
por: Hautbergue, Guillaume M., et al.
Publicado: (2009) -
Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy
por: Stubbs, Sarah H., et al.
Publicado: (2015) -
HIV-1 Rev protein specifies the viral RNA export pathway by suppressing TAP/NXF1 recruitment
por: Taniguchi, Ichiro, et al.
Publicado: (2014) -
NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins
por: Takano, Keizo, et al.
Publicado: (2007) -
ORC interacts with THSC/TREX-2 and its subunits promote Nxf1 association with mRNP and mRNA export in Drosophila
por: Kopytova, Daria, et al.
Publicado: (2016)