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Leishmania actin binds and nicks kDNA as well as inhibits decatenation activity of type II topoisomerase

Leishmania actin (LdACT) is an unconventional form of eukaryotic actin in that it markedly differs from other actins in terms of its filament forming as well as toxin and DNase-1-binding properties. Besides being present in the cytoplasm, cortical regions, flagellum and nucleus, it is also present i...

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Detalles Bibliográficos
Autores principales:	Kapoor, Prabodh, Kumar, Ashutosh, Naik, Rangeetha, Ganguli, Munia, Siddiqi, Mohammad I., Sahasrabuddhe, Amogh A., Gupta, Chhitar M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879525/ https://www.ncbi.nlm.nih.gov/pubmed/20147461 http://dx.doi.org/10.1093/nar/gkq051

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