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Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

Non-homologous end-joining (NHEJ) and homologous recombination repair (HRR), contribute to repair ionizing radiation (IR)-induced DNA double-strand breaks (DSBs). Mre11 binding to DNA is the first step for activating HRR and Ku binding to DNA is the first step for initiating NHEJ. High-linear energy...

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Detalles Bibliográficos
Autores principales:	Wang, Hongyan, Zhang, Xiangming, Wang, Ping, Yu, Xiaoyan, Essers, Jeroen, Chen, David, Kanaar, Roland, Takeda, Shunichi, Wang, Ya
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879532/ https://www.ncbi.nlm.nih.gov/pubmed/20150414 http://dx.doi.org/10.1093/nar/gkq069

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