Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

There is a strong association between BRCA1 mutation carrier status and estrogen receptor-negative breast cancer. This has led to the idea that estrogen receptor-positive breast cancers in BRCA1 mutation carriers may be incidental or sporadic in nature and not as a direct result of BRCA1 dysfunction...

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Detalles Bibliográficos
Autores principales: Lakhani, Sunil R, Khanna, Kum Kum, Chenevix-Trench, Georgia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879558/
https://www.ncbi.nlm.nih.gov/pubmed/20346095
http://dx.doi.org/10.1186/bcr2483
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author Lakhani, Sunil R
Khanna, Kum Kum
Chenevix-Trench, Georgia
author_facet Lakhani, Sunil R
Khanna, Kum Kum
Chenevix-Trench, Georgia
author_sort Lakhani, Sunil R
collection PubMed
description There is a strong association between BRCA1 mutation carrier status and estrogen receptor-negative breast cancer. This has led to the idea that estrogen receptor-positive breast cancers in BRCA1 mutation carriers may be incidental or sporadic in nature and not as a direct result of BRCA1 dysfunction. A recent paper in Breast Cancer Research challenges this view.
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spelling pubmed-28795582010-09-19 Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic? Lakhani, Sunil R Khanna, Kum Kum Chenevix-Trench, Georgia Breast Cancer Res Editorial There is a strong association between BRCA1 mutation carrier status and estrogen receptor-negative breast cancer. This has led to the idea that estrogen receptor-positive breast cancers in BRCA1 mutation carriers may be incidental or sporadic in nature and not as a direct result of BRCA1 dysfunction. A recent paper in Breast Cancer Research challenges this view. BioMed Central 2010 2010-03-19 /pmc/articles/PMC2879558/ /pubmed/20346095 http://dx.doi.org/10.1186/bcr2483 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Editorial
Lakhani, Sunil R
Khanna, Kum Kum
Chenevix-Trench, Georgia
Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title_full Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title_fullStr Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title_full_unstemmed Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title_short Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?
title_sort are estrogen receptor-positive breast cancers in brca1 mutation carriers sporadic?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879558/
https://www.ncbi.nlm.nih.gov/pubmed/20346095
http://dx.doi.org/10.1186/bcr2483
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