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Desmoplastic Melanoma: Report of 5 Cases

Background. The clinical presentation of desmoplastic melanoma is often challenging. We report the experience of the Melanoma Unit of Spedali Civili University Hospital of Brescia, Italy. Method. Study subjects were drawn from 1770 patients with histologica confirmed melanoma. Within this group, des...

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Detalles Bibliográficos
Autores principales: Manganoni, A. M., Farisoglio, C., Bassissi, S., Braga, D., Facchetti, F., Ungari, M., Calzavara-Pinton, P. G.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879601/
https://www.ncbi.nlm.nih.gov/pubmed/20585483
http://dx.doi.org/10.1155/2009/679010
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author Manganoni, A. M.
Farisoglio, C.
Bassissi, S.
Braga, D.
Facchetti, F.
Ungari, M.
Calzavara-Pinton, P. G.
author_facet Manganoni, A. M.
Farisoglio, C.
Bassissi, S.
Braga, D.
Facchetti, F.
Ungari, M.
Calzavara-Pinton, P. G.
author_sort Manganoni, A. M.
collection PubMed
description Background. The clinical presentation of desmoplastic melanoma is often challenging. We report the experience of the Melanoma Unit of Spedali Civili University Hospital of Brescia, Italy. Method. Study subjects were drawn from 1770 patients with histologica confirmed melanoma. Within this group, desmoplastic melanoma developed in 5 patients. For each diagnosed melanoma, histological characteristics, treatment, and outcomes were evaluated. Results. Of the 5 patients described in this study, 2 were males and 3 females. The average age was 62.4 years ranging from 56 to 68 years. Breslow thickness ranged from 2.1 to 12 mm with a mean thickness of 5.8 mm. Primary treatment of 5 patients included a wide local excision of their primary lesions. Conclusions. Desmoplastic melanoma is a rare neoplasm which clinically may mimic other tumours or cutaneous infiltrate of uncertain significance. The diagnosis is hiastopathological and radical resection is necessary.
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spelling pubmed-28796012010-06-28 Desmoplastic Melanoma: Report of 5 Cases Manganoni, A. M. Farisoglio, C. Bassissi, S. Braga, D. Facchetti, F. Ungari, M. Calzavara-Pinton, P. G. Dermatol Res Pract Clinical Study Background. The clinical presentation of desmoplastic melanoma is often challenging. We report the experience of the Melanoma Unit of Spedali Civili University Hospital of Brescia, Italy. Method. Study subjects were drawn from 1770 patients with histologica confirmed melanoma. Within this group, desmoplastic melanoma developed in 5 patients. For each diagnosed melanoma, histological characteristics, treatment, and outcomes were evaluated. Results. Of the 5 patients described in this study, 2 were males and 3 females. The average age was 62.4 years ranging from 56 to 68 years. Breslow thickness ranged from 2.1 to 12 mm with a mean thickness of 5.8 mm. Primary treatment of 5 patients included a wide local excision of their primary lesions. Conclusions. Desmoplastic melanoma is a rare neoplasm which clinically may mimic other tumours or cutaneous infiltrate of uncertain significance. The diagnosis is hiastopathological and radical resection is necessary. Hindawi Publishing Corporation 2009 2009-11-30 /pmc/articles/PMC2879601/ /pubmed/20585483 http://dx.doi.org/10.1155/2009/679010 Text en Copyright © 2009 A. M. Manganoni et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Manganoni, A. M.
Farisoglio, C.
Bassissi, S.
Braga, D.
Facchetti, F.
Ungari, M.
Calzavara-Pinton, P. G.
Desmoplastic Melanoma: Report of 5 Cases
title Desmoplastic Melanoma: Report of 5 Cases
title_full Desmoplastic Melanoma: Report of 5 Cases
title_fullStr Desmoplastic Melanoma: Report of 5 Cases
title_full_unstemmed Desmoplastic Melanoma: Report of 5 Cases
title_short Desmoplastic Melanoma: Report of 5 Cases
title_sort desmoplastic melanoma: report of 5 cases
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879601/
https://www.ncbi.nlm.nih.gov/pubmed/20585483
http://dx.doi.org/10.1155/2009/679010
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