Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

It is now established that most of the ∼800 G-protein-coupled receptors (GPCRs) are regulated by phosphorylation in a process that results in the recruitment of arrestins, leading to receptor desensitization and the activation of arrestin-dependent processes. This generalized view of GPCR regulation...

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Detalles Bibliográficos
Autores principales: Tobin, Andrew B., Butcher, Adrian J., Kong, Kok Choi
Formato: Texto
Lenguaje:English
Publicado: Published By Elsevier In Association With The International Union Of Pharmacology 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880250/
https://www.ncbi.nlm.nih.gov/pubmed/18606460
http://dx.doi.org/10.1016/j.tips.2008.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880250/
https://www.ncbi.nlm.nih.gov/pubmed/18606460
http://dx.doi.org/10.1016/j.tips.2008.05.006

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