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Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
It is now established that most of the ∼800 G-protein-coupled receptors (GPCRs) are regulated by phosphorylation in a process that results in the recruitment of arrestins, leading to receptor desensitization and the activation of arrestin-dependent processes. This generalized view of GPCR regulation...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Published By Elsevier In Association With The International Union Of Pharmacology
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880250/ https://www.ncbi.nlm.nih.gov/pubmed/18606460 http://dx.doi.org/10.1016/j.tips.2008.05.006 |