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Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury
BACKGROUND: The administration of the ketone bodies hydroxybutyrate and acetoacetate is known to exert a protective effect against metabolic disorders associated with cerebral pathologies. This suggests that the enhancement of their endogenous production might be a rational therapeutic approach. Ket...
Autores principales: | Cornille, Emilie, Abou-Hamdan, Mhamad, Khrestchatisky, Michel, Nieoullon, André, de Reggi, Max, Gharib, Bouchra |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880308/ https://www.ncbi.nlm.nih.gov/pubmed/20416081 http://dx.doi.org/10.1186/1471-2202-11-51 |
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