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The Use of Glycerol-Preserved Corneas in the Developing World

Corneal opacity is the third leading cause of blindness in the developing world and encompasses a wide variety of infectious, inflammatory and degenerative eye diseases. Most caes of corneal blindness are treatable with partial or full-thickness keratoplasty, provided adequate corneal tissue and sur...

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Autores principales: Feilmeier, Michael R., Tabin, Geoffrey C., Williams, Lloyd, Oliva, Matt
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880372/
https://www.ncbi.nlm.nih.gov/pubmed/20543935
http://dx.doi.org/10.4103/0974-9233.61215
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author Feilmeier, Michael R.
Tabin, Geoffrey C.
Williams, Lloyd
Oliva, Matt
author_facet Feilmeier, Michael R.
Tabin, Geoffrey C.
Williams, Lloyd
Oliva, Matt
author_sort Feilmeier, Michael R.
collection PubMed
description Corneal opacity is the third leading cause of blindness in the developing world and encompasses a wide variety of infectious, inflammatory and degenerative eye diseases. Most caes of corneal blindness are treatable with partial or full-thickness keratoplasty, provided adequate corneal tissue and surgical skill is available. However, access to sightrestoring keratoplasty in developing countries is limited by the lack of developed eye banking networks and a critical shortage of tissue suitable for transplantation. Beyond the developed world, corneal transplantation using fresh corneal tissue (FCT) is further hindered by unreliable storage and transportation facilities, unorganized distribution networks, the cost-prohibitive nature of imported tissue, unreliable compliance with medications and follow-up instructions and inadequate health and education services. Glycerol-preserved corneas overcome many of these limitations inherent to the use of FCT. As surgical innovation in lamellar corneal surgery expands the potential use of acellular corneal tissue, long-term preservation techniques are being revisited as a way to increase availability of corneal tissue to corneal surgeons throughout the developing world. Herein, we discuss the advantages of using and the applications for glycerol-preserved corneal tissue throughout the developing world.
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spelling pubmed-28803722010-06-11 The Use of Glycerol-Preserved Corneas in the Developing World Feilmeier, Michael R. Tabin, Geoffrey C. Williams, Lloyd Oliva, Matt Middle East Afr J Ophthalmol Cornea/Refractive Update Corneal opacity is the third leading cause of blindness in the developing world and encompasses a wide variety of infectious, inflammatory and degenerative eye diseases. Most caes of corneal blindness are treatable with partial or full-thickness keratoplasty, provided adequate corneal tissue and surgical skill is available. However, access to sightrestoring keratoplasty in developing countries is limited by the lack of developed eye banking networks and a critical shortage of tissue suitable for transplantation. Beyond the developed world, corneal transplantation using fresh corneal tissue (FCT) is further hindered by unreliable storage and transportation facilities, unorganized distribution networks, the cost-prohibitive nature of imported tissue, unreliable compliance with medications and follow-up instructions and inadequate health and education services. Glycerol-preserved corneas overcome many of these limitations inherent to the use of FCT. As surgical innovation in lamellar corneal surgery expands the potential use of acellular corneal tissue, long-term preservation techniques are being revisited as a way to increase availability of corneal tissue to corneal surgeons throughout the developing world. Herein, we discuss the advantages of using and the applications for glycerol-preserved corneal tissue throughout the developing world. Medknow Publications 2010 /pmc/articles/PMC2880372/ /pubmed/20543935 http://dx.doi.org/10.4103/0974-9233.61215 Text en © Middle East African Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cornea/Refractive Update
Feilmeier, Michael R.
Tabin, Geoffrey C.
Williams, Lloyd
Oliva, Matt
The Use of Glycerol-Preserved Corneas in the Developing World
title The Use of Glycerol-Preserved Corneas in the Developing World
title_full The Use of Glycerol-Preserved Corneas in the Developing World
title_fullStr The Use of Glycerol-Preserved Corneas in the Developing World
title_full_unstemmed The Use of Glycerol-Preserved Corneas in the Developing World
title_short The Use of Glycerol-Preserved Corneas in the Developing World
title_sort use of glycerol-preserved corneas in the developing world
topic Cornea/Refractive Update
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880372/
https://www.ncbi.nlm.nih.gov/pubmed/20543935
http://dx.doi.org/10.4103/0974-9233.61215
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