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Maturation of GABAergic Inhibition Promotes Strengthening of Temporally Coherent Inputs among Convergent Pathways

Spike-timing-dependent plasticity (STDP), a form of Hebbian plasticity, is inherently stabilizing. Whether and how GABAergic inhibition influences STDP is not well understood. Using a model neuron driven by converging inputs modifiable by STDP, we determined that a sufficient level of inhibition was...

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Detalles Bibliográficos
Autores principales: Kuhlman, Sandra J., Lu, Jiangteng, Lazarus, Matthew S., Huang, Z. Josh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880567/
https://www.ncbi.nlm.nih.gov/pubmed/20532211
http://dx.doi.org/10.1371/journal.pcbi.1000797