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Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method
Chemical reaction networks (CRNs) are susceptible to mathematical modelling. The dynamic behavior of CRNs can be investigated by solving the polynomial equations derived from its structure. However, simple CRN give rise to non-linear polynomials that are difficult to resolve. Here we propose a proce...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880584/ https://www.ncbi.nlm.nih.gov/pubmed/20532219 http://dx.doi.org/10.1371/journal.pone.0010823 |
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author | Martínez-Forero, Ivan Peláez-López, Antonio Villoslada, Pablo |
author_facet | Martínez-Forero, Ivan Peláez-López, Antonio Villoslada, Pablo |
author_sort | Martínez-Forero, Ivan |
collection | PubMed |
description | Chemical reaction networks (CRNs) are susceptible to mathematical modelling. The dynamic behavior of CRNs can be investigated by solving the polynomial equations derived from its structure. However, simple CRN give rise to non-linear polynomials that are difficult to resolve. Here we propose a procedure to locate the steady states of CRNs from a formula derived through algebraic geometry methods. We have applied this procedure to define the steady states of a classic CRN that exhibits instability, and to a model of programmed cell death. |
format | Text |
id | pubmed-2880584 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-28805842010-06-07 Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method Martínez-Forero, Ivan Peláez-López, Antonio Villoslada, Pablo PLoS One Research Article Chemical reaction networks (CRNs) are susceptible to mathematical modelling. The dynamic behavior of CRNs can be investigated by solving the polynomial equations derived from its structure. However, simple CRN give rise to non-linear polynomials that are difficult to resolve. Here we propose a procedure to locate the steady states of CRNs from a formula derived through algebraic geometry methods. We have applied this procedure to define the steady states of a classic CRN that exhibits instability, and to a model of programmed cell death. Public Library of Science 2010-06-03 /pmc/articles/PMC2880584/ /pubmed/20532219 http://dx.doi.org/10.1371/journal.pone.0010823 Text en Martínez-Foreroet al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Martínez-Forero, Ivan Peláez-López, Antonio Villoslada, Pablo Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title | Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title_full | Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title_fullStr | Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title_full_unstemmed | Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title_short | Steady State Detection of Chemical Reaction Networks Using a Simplified Analytical Method |
title_sort | steady state detection of chemical reaction networks using a simplified analytical method |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880584/ https://www.ncbi.nlm.nih.gov/pubmed/20532219 http://dx.doi.org/10.1371/journal.pone.0010823 |
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