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Vicrostatin – An Anti-Invasive Multi-Integrin Targeting Chimeric Disintegrin with Tumor Anti-Angiogenic and Pro-Apoptotic Activities

Similar to other integrin-targeting strategies, disintegrins have previously shown good efficacy in animal cancer models with favorable pharmacological attributes and translational potential. Nonetheless, these polypeptides are notoriously difficult to produce recombinantly due to their particular s...

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Detalles Bibliográficos
Autores principales:	Minea, Radu O., Helchowski, Corey M., Zidovetzki, Samuel J., Costa, Fritz K., Swenson, Stephen D., Markland, Francis S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880590/ https://www.ncbi.nlm.nih.gov/pubmed/20532165 http://dx.doi.org/10.1371/journal.pone.0010929

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