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LINE-1 methylation is inherited in familial testicular cancer kindreds
BACKGROUND: Testicular germ cell tumors (TGCT) are the most frequent cancers among young men. There is a clear familial component to TGCT etiology, but no high-penetrance susceptibility gene has been identified. Epigenetic aberrations of the genome represent an alternative mechanism for cancer susce...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880977/ https://www.ncbi.nlm.nih.gov/pubmed/20478068 http://dx.doi.org/10.1186/1471-2350-11-77 |