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Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4
BACKGROUND: Chemokine SDF1α and its unique receptor CXCR4 have been implicated in organ-specific metastases of many cancers including breast cancer. Hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. We hypothesized that hypoxia would upregulate CXCR4 expre...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880996/ https://www.ncbi.nlm.nih.gov/pubmed/20492653 http://dx.doi.org/10.1186/1471-2407-10-225 |