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Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features
BACKGROUND: Most previous studies of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been conducted on a relatively small numbers of CpG sites. In the present study we performed comprehensive DNA methylation profiling of CRC with the aim of characterizing CIMP subgroups. M...
Autores principales: | Ang, Pei Woon, Loh, Marie, Liem, Natalia, Lim, Pei Li, Grieu, Fabienne, Vaithilingam, Aparna, Platell, Cameron, Yong, Wei Peng, Iacopetta, Barry, Soong, Richie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880997/ https://www.ncbi.nlm.nih.gov/pubmed/20492682 http://dx.doi.org/10.1186/1471-2407-10-227 |
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