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Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities

BACKGROUND: The major toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) appear to result from dysregulation of mRNA levels mediated by the aryl hydrocarbon receptor (AHR). Dioxin-like chemicals alter expression of numerous genes in liver, but it remains unknown which lie in pathways leadin...

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Detalles Bibliográficos
Autores principales:	Moffat, Ivy D, Boutros, Paul C, Chen, Hanbo, Okey, Allan B, Pohjanvirta, Raimo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881023/ https://www.ncbi.nlm.nih.gov/pubmed/20420666 http://dx.doi.org/10.1186/1471-2164-11-263

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