Prostaglandin-E(2) is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner

Excessive ultraviolet radiation (UVR) exposure induces erythema, mediated in part by prostaglandin-E(2) (PGE(2)). While keratinocytes are a major PGE(2) source, epidermal melanocytes (EM) also express PGE(2)-production machinery. It is unclear whether EM-produced PGE(2) contributes to UVR-induced sk...

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Detalles Bibliográficos
Autores principales: Gledhill, Karl, Rhodes, Lesley E, Brownrigg, Margaret, Haylett, Ann K, Masoodi, Mojgan, Thody, Anthony J, Nicolaou, Anna, Tobin, Desmond J
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881306/
https://www.ncbi.nlm.nih.gov/pubmed/20236442
http://dx.doi.org/10.1111/j.1755-148X.2010.00696.x

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