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Recognition of beta-structural motifs using hidden Markov models trained with simulated evolution
Motivation: One of the most successful methods to date for recognizing protein sequences that are evolutionarily related, has been profile hidden Markov models. However, these models do not capture pairwise statistical preferences of residues that are hydrogen bonded in β-sheets. We thus explore met...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881384/ https://www.ncbi.nlm.nih.gov/pubmed/20529918 http://dx.doi.org/10.1093/bioinformatics/btq199 |