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Robust unmixing of tumor states in array comparative genomic hybridization data

Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness and eventually metastasis. It is hoped that by identifying the common patterns of mutations underlying major cancer sub-types, we can better understand t...

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Detalles Bibliográficos
Autores principales: Tolliver, David, Tsourakakis, Charalampos, Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881397/
https://www.ncbi.nlm.nih.gov/pubmed/20529894
http://dx.doi.org/10.1093/bioinformatics/btq213