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UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes
Interactions of the ESCRT complexes are critical for endosomal trafficking. We identify two domains with potential significance for this process. The MABP domain present in metazoan ESCRT-I/MVB12 subunits, Crag, a regulator of protein sorting, and bacterial pore-forming proteins might mediate novel...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881412/ https://www.ncbi.nlm.nih.gov/pubmed/20448139 http://dx.doi.org/10.1093/bioinformatics/btq235 |