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Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: Similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"
Caveolin-1 (-/-) null stromal cells are a novel genetic model for cancer-associated fibroblasts and myofibroblasts. Here, we used an unbiased informatics analysis of transcriptional gene profiling to show that Cav-1 (-/-) bone-marrow derived stromal cells bear a striking resemblance to the activated...
Autores principales: | Pavlides, Stephanos, Tsirigos, Aristotelis, Vera, Iset, Flomenberg, Neal, Frank, Philippe G., Casimiro, Mathew C., Wang, Chenguang, Pestell, Richard G., Martinez-Outschoorn, Ubaldo E., Howell, Anthony, Sotgia, Federica, Lisanti, Michael P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881509/ https://www.ncbi.nlm.nih.gov/pubmed/20442453 |
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