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Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels
The etiology of pituitary adenomas remains largely unknown, with the exception of involvement of estrogens in the formation of prolactinomas. We have examined the molecular pathogenesis of prolactin-producing pituitary adenomas in transgenic female mice expressing the human choriongonadotropin (hCG)...
Autores principales: | Ahtiainen, Petteri, Sharp, Victoria, Rulli, Susana B, Rivero-Müller, Adolfo, Mamaeva, Veronika, Röyttä, Matias, Huhtaniemi, Ilpo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for Endocrinology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881531/ https://www.ncbi.nlm.nih.gov/pubmed/20453081 http://dx.doi.org/10.1677/ERC-10-0016 |
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