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Nucleic Acid Template and the Risk of a PCR-Induced HIV-1 Drug Resistance Mutation

BACKGROUND: The HIV-1 nucleoside RT inhibitor (NRTI)-resistance mutation, K65R confers intermediate to high-level resistance to the NRTIs abacavir, didanosine, emtricitabine, lamivudine, and tenofovir; and low-level resistance to stavudine. Several lines of evidence suggest that K65R is more common...

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Detalles Bibliográficos
Autores principales:	Varghese, Vici, Wang, Elijah, Babrzadeh, Farbod, Bachmann, Michael H., Shahriar, Rajin, Liu, Tommy, Mappala, Svetlana Jean M., Gharizadeh, Baback, Fessel, W. Jeffrey, Katzenstein, David, Kassaye, Seble, Shafer, Robert W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881873/ https://www.ncbi.nlm.nih.gov/pubmed/20539818 http://dx.doi.org/10.1371/journal.pone.0010992

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