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Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice
BACKGROUND: Cell proliferation in all rapidly renewing mammalian tissues follows a circadian rhythm that is often disrupted in advanced-stage tumors. Epidemiologic studies have revealed a clear link between disruption of circadian rhythms and cancer development in humans. Mice lacking the circadian...
Autores principales: | Lee, Susie, Donehower, Lawrence A., Herron, Alan J., Moore, David D., Fu, Loning |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881876/ https://www.ncbi.nlm.nih.gov/pubmed/20539819 http://dx.doi.org/10.1371/journal.pone.0010995 |
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