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Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia
BACKGROUND: Chronic lymphocytic leukemia (CLL) cells are often affected by genomic aberrations targeting key regulatory genes. Although fludarabine is the standard first line therapy to treat CLL, only few data are available about the resistance of B cells to this purine nucleoside analog in vivo. H...
Autores principales: | Moussay, Etienne, Palissot, Valérie, Vallar, Laurent, Poirel, Hélène A, Wenner, Thomas, El Khoury, Victoria, Aouali, Nasséra, Van Moer, Kris, Leners, Bernadette, Bernardin, François, Muller, Arnaud, Cornillet-Lefebvre, Pascale, Delmer, Alain, Duhem, Caroline, Ries, Fernand, van Dyck, Eric, Berchem, Guy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881880/ https://www.ncbi.nlm.nih.gov/pubmed/20487546 http://dx.doi.org/10.1186/1476-4598-9-115 |
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