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Communicating serum chemical concentrations to study participants: follow up survey

BACKGROUND: A considerable literature now supports the importance of effective communication with study participants, including how best to develop communication plans focusing on the uncertainty of health risks associated with particular environmental exposures. Strategies for communicating individ...

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Autores principales: Buck, Alexandra J, Vena, John E, McGuinness, Bridget M, Cooney, Maureen A, Louis, Germaine M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881911/
https://www.ncbi.nlm.nih.gov/pubmed/20441591
http://dx.doi.org/10.1186/1476-069X-9-20
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author Buck, Alexandra J
Vena, John E
McGuinness, Bridget M
Cooney, Maureen A
Louis, Germaine M
author_facet Buck, Alexandra J
Vena, John E
McGuinness, Bridget M
Cooney, Maureen A
Louis, Germaine M
author_sort Buck, Alexandra J
collection PubMed
description BACKGROUND: A considerable literature now supports the importance of effective communication with study participants, including how best to develop communication plans focusing on the uncertainty of health risks associated with particular environmental exposures. Strategies for communicating individual concentrations of environmental chemicals in human biological samples in the absence of clearly established safe or hazardous levels have been discussed from a conceptual basis and to a lesser extent from an empirical basis. We designed and evaluated an empirically based communication strategy for women of reproductive age who previously participated in a prospective study focusing on persistent environmental chemicals and reproductive outcomes. METHODS: A cohort of women followed from preconception through pregnancy or up to 12 menstrual cycles without pregnancy was given their individual serum concentrations for lead, dichloro-2,2-bisp-chlorophenyl ethylene, and select polychlorinated biphenyl congeners. Two versions of standardized letters were prepared depending upon women's exposure status, which was characterized as low or high. Letters included an introduction, individual concentrations, population reference values and guidance for minimizing future exposures. Participants were actively monitored for any questions or concerns following receipt of letters. RESULTS: Ninety-eight women were sent letters informing them of their individual concentrations to select study chemicals. None of the 89 (91%) participating women irrespective of exposure status contacted the research team with questions or concerns about communicated exposures despite an invitation to do so. CONCLUSIONS: Our findings suggest that study participants can be informed about their individual serum concentrations without generating unnecessary concern.
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spelling pubmed-28819112010-06-08 Communicating serum chemical concentrations to study participants: follow up survey Buck, Alexandra J Vena, John E McGuinness, Bridget M Cooney, Maureen A Louis, Germaine M Environ Health Research BACKGROUND: A considerable literature now supports the importance of effective communication with study participants, including how best to develop communication plans focusing on the uncertainty of health risks associated with particular environmental exposures. Strategies for communicating individual concentrations of environmental chemicals in human biological samples in the absence of clearly established safe or hazardous levels have been discussed from a conceptual basis and to a lesser extent from an empirical basis. We designed and evaluated an empirically based communication strategy for women of reproductive age who previously participated in a prospective study focusing on persistent environmental chemicals and reproductive outcomes. METHODS: A cohort of women followed from preconception through pregnancy or up to 12 menstrual cycles without pregnancy was given their individual serum concentrations for lead, dichloro-2,2-bisp-chlorophenyl ethylene, and select polychlorinated biphenyl congeners. Two versions of standardized letters were prepared depending upon women's exposure status, which was characterized as low or high. Letters included an introduction, individual concentrations, population reference values and guidance for minimizing future exposures. Participants were actively monitored for any questions or concerns following receipt of letters. RESULTS: Ninety-eight women were sent letters informing them of their individual concentrations to select study chemicals. None of the 89 (91%) participating women irrespective of exposure status contacted the research team with questions or concerns about communicated exposures despite an invitation to do so. CONCLUSIONS: Our findings suggest that study participants can be informed about their individual serum concentrations without generating unnecessary concern. BioMed Central 2010-05-04 /pmc/articles/PMC2881911/ /pubmed/20441591 http://dx.doi.org/10.1186/1476-069X-9-20 Text en Copyright ©2010 Buck et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Buck, Alexandra J
Vena, John E
McGuinness, Bridget M
Cooney, Maureen A
Louis, Germaine M
Communicating serum chemical concentrations to study participants: follow up survey
title Communicating serum chemical concentrations to study participants: follow up survey
title_full Communicating serum chemical concentrations to study participants: follow up survey
title_fullStr Communicating serum chemical concentrations to study participants: follow up survey
title_full_unstemmed Communicating serum chemical concentrations to study participants: follow up survey
title_short Communicating serum chemical concentrations to study participants: follow up survey
title_sort communicating serum chemical concentrations to study participants: follow up survey
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881911/
https://www.ncbi.nlm.nih.gov/pubmed/20441591
http://dx.doi.org/10.1186/1476-069X-9-20
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