N′(1),N′(3)-Dimethyl-N′(1),N′(3)-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS)

Cisplatin is an important chemotherapeutic agent in lung cancer treatment. The mechanism of drug resistance to cisplatin is complex and historically has been difficult to overcome. We report here that cisplatin resistant lung cancer cell lines possess high basal levels of reactive oxygen species (RO...

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Detalles Bibliográficos
Autores principales: Wangpaichitr, Medhi, Wu, Chunjing, You, Min, Maher, Johnathan C., Dinh, Vy, Feun, Lynn G., Savaraj, Niramol
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882109/
https://www.ncbi.nlm.nih.gov/pubmed/20535236
http://dx.doi.org/10.3390/cancers1010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882109/
https://www.ncbi.nlm.nih.gov/pubmed/20535236
http://dx.doi.org/10.3390/cancers1010023

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