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Role of 4-1BB Receptor in the Control Played by CD8(+) T Cells on IFN-γ Production by Mycobacterium tuberculosis Antigen-Specific CD4(+) T Cells
BACKGROUND: Antigen-specific IFN-γ producing CD4(+) T cells are the main mediators of protection against Mycobacterium tuberculosis infection both under natural conditions and following vaccination. However these cells are responsible for lung damage and poor vaccine efficacy when not tightly contro...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882340/ https://www.ncbi.nlm.nih.gov/pubmed/20544034 http://dx.doi.org/10.1371/journal.pone.0011019 |