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Evaluating the Cellular Targets of Anti-4-1BB Agonist Antibody during Immunotherapy of a Pre-Established Tumor in Mice

BACKGROUND: Manipulation of the immune system represents a promising avenue for cancer therapy. Rational advances in immunotherapy of cancer will require an understanding of the precise correlates of protection. Agonistic antibodies against the tumor necrosis factor receptor family member 4-1BB are...

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Detalles Bibliográficos
Autores principales: Lin, Gloria H. Y., Liu, Yuanqing, Ambagala, Thanuja, Kwon, Byoung S., Ohashi, Pamela S., Watts, Tania H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882368/
https://www.ncbi.nlm.nih.gov/pubmed/20543982
http://dx.doi.org/10.1371/journal.pone.0011003