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Evaluating the Cellular Targets of Anti-4-1BB Agonist Antibody during Immunotherapy of a Pre-Established Tumor in Mice
BACKGROUND: Manipulation of the immune system represents a promising avenue for cancer therapy. Rational advances in immunotherapy of cancer will require an understanding of the precise correlates of protection. Agonistic antibodies against the tumor necrosis factor receptor family member 4-1BB are...
Autores principales: | Lin, Gloria H. Y., Liu, Yuanqing, Ambagala, Thanuja, Kwon, Byoung S., Ohashi, Pamela S., Watts, Tania H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882368/ https://www.ncbi.nlm.nih.gov/pubmed/20543982 http://dx.doi.org/10.1371/journal.pone.0011003 |
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