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Enhanced prefrontal serotonin 5-HT(1A) currents in a mouse model of Williams-Beuren syndrome with low innate anxiety

Williams-Beuren syndrome (WBS) is a neurodevelopmental disorder caused by the hemizygous deletion of 28 genes on chromosome 7, including the general transcription factor GTF2IRD1. Mice either hemizygously (Gtf2ird1 (+/−)) or homozygously (Gtf2ird1 (−/−)) deleted for this transcription factor exhibit...

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Detalles Bibliográficos
Autores principales: Proulx, Éliane, Young, Edwin J., Osborne, Lucy R., Lambe, Evelyn K.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882561/
https://www.ncbi.nlm.nih.gov/pubmed/20585377
http://dx.doi.org/10.1007/s11689-010-9044-5

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