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A Screen for Endocytic Motifs

Sorting signals for cargo selection into coated vesicles are usually in the form of short linear motifs. Three motifs for clathrin-mediated endocytosis have been identified: YXXΦ, [D/E]XXXL[L/I] and FXNPXY. To search for new endocytic motifs, we made a library of CD8 chimeras with random sequences i...

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Detalles Bibliográficos
Autores principales: Kozik, Patrycja, Francis, Richard W, Seaman, Matthew N J, Robinson, Margaret S
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882754/
https://www.ncbi.nlm.nih.gov/pubmed/20214754
http://dx.doi.org/10.1111/j.1600-0854.2010.01056.x