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Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD

BACKGROUND: Multidrug resistance-associated protein-1 (MRP1) protects against oxidative stress and toxic compounds generated by cigarette smoking, which is the main risk factor for chronic obstructive pulmonary disease (COPD). We have previously shown that single nucleotide polymorphisms (SNPs) in M...

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Detalles Bibliográficos
Autores principales:	Budulac, Simona E, Postma, Dirkje S, Hiemstra, Pieter S, Kunz, Lisette IZ, Siedlinski, Mateusz, Smit, Henriette A, Vonk, Judith M, Rutgers, Bea, Timens, Wim, Boezen, H Marike
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882908/ https://www.ncbi.nlm.nih.gov/pubmed/20487524 http://dx.doi.org/10.1186/1465-9921-11-60

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