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A Genome-Wide Association Study of Optic Disc Parameters
The optic nerve head is involved in many ophthalmic disorders, including common diseases such as myopia and open-angle glaucoma. Two of the most important parameters are the size of the optic disc area and the vertical cup-disc ratio (VCDR). Both are highly heritable but genetically largely undeterm...
Autores principales: | Ramdas, Wishal D., van Koolwijk, Leonieke M. E., Ikram, M. Kamran, Jansonius, Nomdo M., de Jong, Paulus T. V. M., Bergen, Arthur A. B., Isaacs, Aaron, Amin, Najaf, Aulchenko, Yurii S., Wolfs, Roger C. W., Hofman, Albert, Rivadeneira, Fernando, Oostra, Ben A., Uitterlinden, Andre G., Hysi, Pirro, Hammond, Christopher J., Lemij, Hans G., Vingerling, Johannes R., Klaver, Caroline C. W., van Duijn, Cornelia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883590/ https://www.ncbi.nlm.nih.gov/pubmed/20548946 http://dx.doi.org/10.1371/journal.pgen.1000978 |
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