Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase

Protein palmitoylation has emerged as an important mechanism for regulating protein trafficking, stability, and protein–protein interactions; however, its relevance to disease processes is not clear. Using a genome-wide, phenotype driven N-ethyl-N-nitrosourea–mediated mutagenesis screen, we identifi...

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Detalles Bibliográficos
Autores principales: Saleem, Amir N., Chen, Yen-Hui, Baek, Hwa Jin, Hsiao, Ya-Wen, Huang, Hong-Wen, Kao, Hsiao-Jung, Liu, Kai-Ming, Shen, Li-Fen, Song, I-wen, Tu, Chen-Pei D., Wu, Jer-Yuarn, Kikuchi, Tateki, Justice, Monica J., Yen, Jeffrey J. Y., Chen, Yuan-Tsong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883605/
https://www.ncbi.nlm.nih.gov/pubmed/20548961
http://dx.doi.org/10.1371/journal.pgen.1000985

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