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BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients’ outcome

BACKGROUND: The significance of BRAF mutations, microsatelite instability (MSI) status and cyclin D1 expression in patients with metastatic colorectal cancer (mCRC) was evaluated. METHODS: Primary tumours from 144 patients treated for mCRC were assessed for BRAF (V600E) mutation, MSI status and cycl...

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Detalles Bibliográficos
Autores principales:	Saridaki, Z, Papadatos-Pastos, D, Tzardi, M, Mavroudis, D, Bairaktari, E, Arvanity, H, Stathopoulos, E, Georgoulias, V, Souglakos, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883698/ https://www.ncbi.nlm.nih.gov/pubmed/20485284 http://dx.doi.org/10.1038/sj.bjc.6605694

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