MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis

AIMS: Vascular smooth muscle cell (VSMC) apoptosis can lead to thinning of the fibrous cap and plaque instability. We previously showed that cell–cell contacts mediated by N-cadherin reduce VSMC apoptosis. This study aimed to determine whether matrix-degrading metalloproteinase (MMP)-dependent N-cad...

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Detalles Bibliográficos
Autores principales: Williams, Helen, Johnson, Jason L., Jackson, Christopher L., White, Stephen J., George, Sarah J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883897/
https://www.ncbi.nlm.nih.gov/pubmed/20139113
http://dx.doi.org/10.1093/cvr/cvq042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883897/
https://www.ncbi.nlm.nih.gov/pubmed/20139113
http://dx.doi.org/10.1093/cvr/cvq042

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