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MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis

AIMS: Vascular smooth muscle cell (VSMC) apoptosis can lead to thinning of the fibrous cap and plaque instability. We previously showed that cell–cell contacts mediated by N-cadherin reduce VSMC apoptosis. This study aimed to determine whether matrix-degrading metalloproteinase (MMP)-dependent N-cad...

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Detalles Bibliográficos
Autores principales:	Williams, Helen, Johnson, Jason L., Jackson, Christopher L., White, Stephen J., George, Sarah J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883897/ https://www.ncbi.nlm.nih.gov/pubmed/20139113 http://dx.doi.org/10.1093/cvr/cvq042

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