Spindly/CCDC99 Is Required for Efficient Chromosome Congression and Mitotic Checkpoint Regulation

Spindly recruits a fraction of cytoplasmic dynein to kinetochores for poleward movement of chromosomes and control of mitotic checkpoint signaling. Here we show that human Spindly is a cell cycle–regulated mitotic phosphoprotein that interacts with the Rod/ZW10/Zwilch (RZZ) complex. The kinetochore...

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Detalles Bibliográficos
Autores principales: Barisic, Marin, Sohm, Bénédicte, Mikolcevic, Petra, Wandke, Cornelia, Rauch, Veronika, Ringer, Thomas, Hess, Michael, Bonn, Günther, Geley, Stephan
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883941/
https://www.ncbi.nlm.nih.gov/pubmed/20427577
http://dx.doi.org/10.1091/mbc.E09-04-0356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883941/
https://www.ncbi.nlm.nih.gov/pubmed/20427577
http://dx.doi.org/10.1091/mbc.E09-04-0356

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