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The (r)evolution of cancer genetics
The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known can...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883958/ https://www.ncbi.nlm.nih.gov/pubmed/20594288 http://dx.doi.org/10.1186/1741-7007-8-74 |
| _version_ | 1782182293814640640 |
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| author | Ciccarelli, Francesca D |
| author_facet | Ciccarelli, Francesca D |
| author_sort | Ciccarelli, Francesca D |
| collection | PubMed |
| description | The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan multicellularity. See research article http://www.biomedcentral.com/1741-7007/8/66 |
| format | Text |
| id | pubmed-2883958 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-28839582010-06-12 The (r)evolution of cancer genetics Ciccarelli, Francesca D BMC Biol Commentary The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan multicellularity. See research article http://www.biomedcentral.com/1741-7007/8/66 BioMed Central 2010-06-11 /pmc/articles/PMC2883958/ /pubmed/20594288 http://dx.doi.org/10.1186/1741-7007-8-74 Text en Copyright ©2010 Ciccarelli; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Commentary Ciccarelli, Francesca D The (r)evolution of cancer genetics |
| title | The (r)evolution of cancer genetics |
| title_full | The (r)evolution of cancer genetics |
| title_fullStr | The (r)evolution of cancer genetics |
| title_full_unstemmed | The (r)evolution of cancer genetics |
| title_short | The (r)evolution of cancer genetics |
| title_sort | (r)evolution of cancer genetics |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883958/ https://www.ncbi.nlm.nih.gov/pubmed/20594288 http://dx.doi.org/10.1186/1741-7007-8-74 |
| work_keys_str_mv | AT ciccarellifrancescad therevolutionofcancergenetics AT ciccarellifrancescad revolutionofcancergenetics |