Mathematical modeling of translation initiation for the estimation of its efficiency to computationally design mRNA sequences with desired expression levels in prokaryotes

BACKGROUND: Within the emerging field of synthetic biology, engineering paradigms have recently been used to design biological systems with novel functionalities. One of the essential challenges hampering the construction of such systems is the need to precisely optimize protein expression levels fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Na, Dokyun, Lee, Sunjae, Lee, Doheon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883959/
https://www.ncbi.nlm.nih.gov/pubmed/20504310
http://dx.doi.org/10.1186/1752-0509-4-71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883959/
https://www.ncbi.nlm.nih.gov/pubmed/20504310
http://dx.doi.org/10.1186/1752-0509-4-71

Ejemplares similares