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Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network
BACKGROUND: Diminished expression or activity of prostate apoptosis response protein 4 (Par-4) has been demonstrated in a number of cancers, although reports on Par-4 expression during colon cancer progression are lacking. An understanding of the molecular events in conjunction with the genetic netw...
Autores principales: | Wang, Bi-Dar, Kline, Christina Leah B, Pastor, Danielle M, Olson, Thomas L, Frank, Bryan, Luu, Truong, Sharma, Arun K, Robertson, Gavin, Weirauch, Matthew T, Patierno, Steven R, Stuart, Joshua M, Irby, Rosalyn B, Lee, Norman H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883962/ https://www.ncbi.nlm.nih.gov/pubmed/20433755 http://dx.doi.org/10.1186/1476-4598-9-98 |
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