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Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene

BACKGROUND: Opioid analgesics such as morphine and meperidine have been used to control moderate to severe pain for many years. However, these opioids have many side effects, including the development of tolerance and dependence after long-term use, which has limited their clinical use. We previousl...

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Detalles Bibliográficos
Autores principales:	Chen, Shiou-Lan, Ma, Hsin-I, Han, Jun-Ming, Lu, Ru-Band, Tao, Pao-Luh, Law, Ping-Yee, Loh, Horace H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883971/ https://www.ncbi.nlm.nih.gov/pubmed/20403204 http://dx.doi.org/10.1186/1423-0127-17-28

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