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Generation of functional CD8+ T Cells by human dendritic cells expressing glypican-3 epitopes

BACKGROUND: Glypican 3 (GPC-3) is an oncofoetal protein that is expressed in most hepatocellular carcinomas (HCC). Since it is a potential target for T cell immunotherapy, we investigated the generation of functional, GPC-3 specific T cells from peripheral blood mononuclear cells (PBMC). METHODS: De...

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Detalles Bibliográficos
Autores principales:	O'Beirne, James, Farzaneh, Farzin, Harrison, Phillip M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883974/ https://www.ncbi.nlm.nih.gov/pubmed/20465843 http://dx.doi.org/10.1186/1756-9966-29-48

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