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Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is a member of the Janus-activated kinase(Jak)/Stat signaling pathway. Abnormal activation of Stat3 plays a critical role in metastasis and invasion in varieties of human tumors including pancreatic cancer. This study aimed to in...

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Detalles Bibliográficos
Autores principales:	Huang, Chen, Yang, Guang, Jiang, Tao, Huang, Kejian, Cao, Jun, Qiu, Zhengjun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883975/ https://www.ncbi.nlm.nih.gov/pubmed/20482858 http://dx.doi.org/10.1186/1756-9966-29-51

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