Peptide Orientation Affects Selectivity in Ion-Exchange Chromatography

Here we demonstrate that separation of proteolytic peptides, having the same net charge and one basic residue, is affected by their specific orientation toward the stationary phase in ion-exchange chromatography. In electrostatic repulsion−hydrophilic interaction chromatography (ERLIC) with an anion...

Descripción completa

Detalles Bibliográficos
Autores principales: Alpert, Andrew J., Petritis, Konstantinos, Kangas, Lars, Smith, Richard D., Mechtler, Karl, Mitulović, Goran, Mohammed, Shabaz, Heck, Albert J. R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884984/
https://www.ncbi.nlm.nih.gov/pubmed/20481592
http://dx.doi.org/10.1021/ac100651k

Ejemplares similares

Ejemplares similares