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Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1

Adeno-associated virus serotype 2 (AAV-2) has been developed as a gene therapy vector. Antibody and cell-mediated immune responses to AAV-2 or AAV-2-transfected cells may confound the therapeutic use of such vectors in clinical practice. In one of the most detailed examinations of AAV-2 immunity in...

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Detalles Bibliográficos
Autores principales:	Madsen, Declan, Cantwell, Emma R., O'Brien, Timothy, Johnson, Patricia A., Mahon, Bernard P.
Formato:	Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2009
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885037/ https://www.ncbi.nlm.nih.gov/pubmed/19641045 http://dx.doi.org/10.1099/vir.0.014175-0

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